Plant Types: Pharmaceutical
Subtypes: API
UNUSED state-of-the-art highly flexible small molecule manufacturing facility constructed in 2011 The facility is capable of producing around 400kg of API per year, allowing for the production of batches from lead to candidate through to Phase III and commercial launch quantities. This is the potential capacity, in a configuration of people working in 2x7h on 5 days, but this tool could be operated on a 24x7 basis if needed, in which case higher levels of output could be achieved. Production capacity remains dependent on the type and number of synthesis steps.
PILOT PLANT • Designed to produce GMP active ingredient batches • 15 reactors (from 100 to 1600 liters) and 5 finishing units (from 10 to 100 kg)
Plant Types: Chemical and Specialty Chemical, Pharmaceutical, Fertilizer and Agrichemical
Subtypes: API
Capacity: ~1,200m3 Total Reactor Capacity
190 Acre API Manufacturing Plant Complex Grimsby, England, UK
This world-class, fully integrated API manufacturing site, formerly operated by Novartis, includes over 1,200m3 of total reactor vessel capacity across three distinct production buildings, available for sale or lease as a whole site or individual buildings for operation in-place. The facility could be utilized for pharmaceutical and animal health API manufacturing or repurposed for specialty/fine chemical manufacturing, flavors and fragrances, or agrochemicals.
VIDEO: https://www.youtube.com/watch?v=AUWUHnAyWos&list=PLRlhdb05DXKR4eyHsLOkB6NzTyh2R4YCE
The site is located adjacent to the river Humber and between the Immingham and Grimsby port facilities, less than 5 minutes from downtown Grimsby, 25 minutes from Humberside Airport, 2.5 hours from Manchester Airport, 3.5 hours from London Heathrow.
Inside the fenceline is approximately 100 acres, with significant development land and infrastructure available inside the fence. There is an additional approximately 90 acres of agricultural land outside the fenceline.
Facility has the capabilities to perform various chemical synthesis, including hydrogenation, Grignard/Friedel-Crafts Reactions, Azide, and Tin Chemistries.
Building 110: Multi-product, Multi-purpose facility (ca. 1993)
Building 120: Mixed High Volume, Multi-Purpose Facility (ca. 1994/2007)
Building 150: High Volume, Multi-Product Facility (ca. 2004/2007)
Each building has its own dedicated solvent storage and recovery, in-process lab spaces, workshops, and offices.
Site Utilities:
The production buildings are supported by the following non-production infrastructure:
Warehousing:
The facility was not used in production of of plant/animal extracts, fermentation, penicilin, beta-lactams, steroids, hormonals, or cytoxic compounds.