190 Acre API Manufacturing Plant ComplexGrimsby, England, UK

This world-class, fully integrated API manufacturing site, formerly operated by Novartis, includes over 1,200m3 of total reactor vessel capacity across three distinct production buildings, available for sale or lease as a whole site or individual buildings for operation in-place. The facility could be utilized for pharmaceutical and animal health API manufacturing or repurposed for specialty/fine chemical manufacturing, flavors and fragrances, or agrochemicals.

Take the 360° Tour:

Building 110, Former Novartis Site, Grimsby

Building 150, Former Novartis Site, Grimsby

VIDEO: https://www.youtube.com/watch?v=AUWUHnAyWos&list=PLRlhdb05DXKR4eyHsLOkB6NzTyh2R4YCE

The site is located adjacent to the river Humber and between the Immingham and Grimsby port facilities, less than 5 minutes from downtown Grimsby, 25 minutes from Humberside Airport, 2.5 hours from Manchester Airport, 3.5 hours from London Heathrow.

Inside the fenceline is approximately 100 acres, with significant development land and infrastructure available inside the fence. There is an additional approximately 90 acres of agricultural land outside the fenceline.

Facility has the capabilities to perform various chemical synthesis, including hydrogenation, Grignard/Friedel-Crafts Reactions, Azide, and Tin Chemistries.

Building 110: Multi-product, Multi-purpose facility (ca. 1993)

• Total Reactor Capacity: 140m3
• Hydrogenation, Crystallization, Centrifugation, Nutsche Filters, Short-Path Distillation, Milling/Blending, Solvent Recovery
• Overhead manifolds and flex piping for production flexibility
• Glass Lined, Hastelloy, and Stainless Steel Equipment

Building 120: Mixed High Volume, Multi-Purpose Facility (ca. 1994/2007)

• Total Reactor Capacity: ~450m3
• 3 dedicated, 3 multi-purpose lines-Hydrogenation, Crystallization, Sublimation, Nutsche Filters, Paddle Dryers, Milling/Blending, Solvent Recovery
• Glass Lined, Hastelloy, and Stainless Steel Equipment

Building 150: High Volume, Multi-Product Facility (ca. 2004/2007)

• 4 Dedicated Process Trains
• Total Reactor Capacity: ~550m3
• Hydrogenation, Crystallization, Centrifugation, Drying, Milling/Blending, Solvent Recovery
• Glass Lined, Hastelloy, and Stainless Steel Equipment

Each building has its own dedicated solvent storage and recovery, in-process lab spaces, workshops, and offices.

Site Utilities:

• 2400m3/day Wastewater (Effluent) Treatment Facility
• 2x4.2MVA grid electricity
• 8000m3/h compressed air
• 3000m3/h nitrogen (by pipeline)
• 4x8MW cooling water capacity
• Towns Water potable supply & 400m3/day borehole (well) water for process cooling
• Previously, there was a CHP plant which has been removed and steam boilers will need to be added to support operations.

The production buildings are supported by the following non-production infrastructure:

• Security Facility
• Administrative Office Building
• 4600m2 (50,000ft2) Engineering Workshop and Offices to support major projects, MRO stores, fabrication, equipment and instrument maintenance, etc.
• 3700m2 (40,000ft2) Lab/R&D Space with sample retain storage facility
• Restaurant/Canteen Building
• Medical Facility/Employee Welfare
• Sports Club and Fields
• Capital Good Stores
• Changeover Warehouses

Warehousing:

• Raw Materials & Intermediate Storage: 3000 pallets
• Solvent (flammable & hazardous) Warehouse: 1930 pallets
• Packaging Storage: 500 pallets
• Finished Goods Storage: 750 pallets
• Cold Storage (-8 deg. C): 320 pallets
• Classified area for sampling / repacking of raw materials: 40 pallets
• Waste Storage: 1200 pallets

The facility was not used in production of of plant/animal extracts, fermentation, penicilin, beta-lactams, steroids, hormonals, or cytoxic compounds.

Pharmaceutical OSD Facility Available

Midwest US Site – cGMP/FDA Facility - Ideal for Tablets, Capsules, Powders, & Packaging

Facility Details

90,000 sq. ft. OSD Manufacturing Site

Designed for tablets, capsules, powders, and sachets, this Oral Solid Dose (OSD) manufacturing facility is immediately available for redeployment/operation. The facility was previously operated under US FDA regulations until its idling in 2025.

From blending and tableting to fluid bed drying, pan coating, and packaging, this facility has it all. With GMP-compliant workflows, serialized packaging lines, a DEA vault, and robust utilities, the system is built for high-output, regulated production with minimal ramp-up.

Suitable Uses

• Pharmaceutical, Nutraceutical and/or animal health manufacturing
• CDMO & Generic Drug Production
• Sachet, Capsule, and Tablet Contract Packaging
• High-volume Dry Blending or Powder Filling

Manufacturing Assets

Dispensing / Weighing

• Sample Thief (Globe Pharma)
• Purified Water Meter (Red Lion Controls)

Milling / Sieving

• Fitzmill Comminutor 1 (Fitzpatrick)
• Fitz DAS06 (Fitzmill variant)

Blending / Mixing

• Gemco 2 50 Cu. Ft. Blender, Slant Cone (Gemco)
• Gemco 3 cu. ft. Blender (Gemco)
• Marion Blender (Marion)
• American Blender (American)
• Tote Blender (Custom Metalcraft)
• Ribbon Blender (SS316)
• Groen Mixer Kettle (Groen)

Precision Dispensing & Weighing Equipment

Granulation

• Glatt GPCG5 Fluid Bed Dryer (functions as granulator/dryer)

Drying (for wet granulation)

• Glatt WSG300 Fluid Bed Dryer with product bowls
• Huebsch Industrial Dryer

Milling & Particle Size Control Equipment

Compression / Tableting

• Kikusui Gemini Tablet Press
• Kikusui Libra Tablet Press
• Pharmaflex Feeders
• Multi-Auger Filler (All-Fill)

Tablet Coating

• Glatt Pro-Coater Coating Pan 1 & 2
• Compulab Coating Pan
• XcellaCoater DXL-60

Encapsulation

• Encapsulator (IMA)

Final Dose Formation Equipment

In-Process Testing (IPT)

• Computrac Moisture Analyzers
• Tablet Deduster (Lyra, Kikusui)
• Infrared Absorption Gauge (Infrared Engineering)
• Errant Tablet Detector (Tri-Tronics)
• Crooked Cap Detector (USL Custom)
• Icore Checkweigher
• All-Fill Checkweigher

Bottling / Blister Packaging

• Can Filler (Continental Can)
• Can Seamer (Panama Can)
• Capper – Resina, Unicap 150, BellatRx
• Cottoner – NJM/CLI
• Retorquer – Resina, NJM
• Labelers – NJM, BellatRx
• MGS Outserter
• Bellmark and Wolke Printers
• Serialization System (Optel)
• Bottle Labeler (NJM/CLI)

Final Quality Control (QC) Testing

• Filter Holders (Advantec)
• Sample Thief (Globe Pharma)
• Purified Water Systems (for microbiological testing)

Storage / Warehousing

• Tote Bins (C.R Daniels, Tote Systems)
• Mini Tote Cart (Ramar Precision)
• Transfer Bins

Utilities & Site Infrastructure

• Compressed Air: 2× 75 HP + 1× 50 HP Atlas Copco systems
• Backup Power: 1500 kW CAT diesel generator (Tier 4, ATS)
• Steam: 125/60/12 PSIG w/ Cleaver Brooks 150 HP boiler (Lo-NOx)
• Chillers: 2× 300T YORK chillers
• Water: 2× USP DI skids (20 GPM + 15 GPM)

Control & Support Systems

• Building Management: Johnson Controls + Honeywell systems
• HVAC: Multiple Trane, AAON, Carrier, Reznor RTUs
• Warehouse Fleet: Walkies, stand-up rider, barrel dumpers
• Material Handling: Tablet lifts, funnel systems, tote bins

Special Features

• Dedicated pre-weigh and dispense room
• Liquid prep room with agitator kettles and floor scales
• Ultrasonic cleaners, tablet dedusters, and moisture analyzers
• DEA vault onsite
• Systematic press, blend, and packaging room organization

Plant Layout Overview

Main Floor: 65,860 Sq. Ft.

Second Floor: 26,794 Sq. Ft.

Total: 92,654 sq. ft.

Why This Plant?

• Accelerate time-to-market: Skip the 24–36 months of design, build, and validation.
• Scale instantly: Full production lines for oral solids, from formulation to final packaging.
• Zero wait for equipment lead times: Everything you need is ready now.
• Flexible acquisition: Take over the plant in situ or move it to your own site.
• Perfect for CDMOs, generics, or nutraceutical manufacturers.

1,170 barrel-per-day Fischer-Tropsch (FT) Gas-to-Liquid (GTL) Wax plant targeting the production of higher-value wax products.

Product Mix:

Naphtha: High purity liquid paraffins targeted for chemical feedstock, or chemicals such as solvents, lighter fluids

Distillate: Zero sulfur and high cetane, ideal performance-enhancing automotive diesel additive, or used as high purity liquid paraffins in chemicals such as solvents, detergents, or drilling fluids

J40 Low Melt and J55 Mid Melt Wax: Low and mid-melting point waxes are primarily used in candles, corrugated board, particle board, tires, PVC additives, pharmaceuticals and personal care and cosmeticsJ75 High Melt Wax: Used in PVC additives for extruders, hot-melt adhesives, inks paints and coatings, candle additives, and personal care and cosmetics

J100 Hard Wax: Used in hot melt adhesives, PVC lubricants, inks, paints and coating additives, asphalt additives, and personal care and cosmetics

• The facility is nearly (75%) finished construction with all new equipment fabricated in 2015.
• The SMR was originally built in 1993 and only operated for about 10 years. It has been completely overhauled and has zero hours since overhaul.
• The two FT reactors are 78,000 sq ft shell and tube exchangers with FT catalyst packed inside the tubes.  The reactors are 11’ diameter with 32’ long tubes which are rated for 500 psig at 500°F.
• All of the steam-generation equipment is included for capturing the FT reaction exotherm.
• Most of the downstream process-contact material of construction is 304Lstainless steel.
• There is no asbestos in this facility.
• This system is located on a major deep-water port with international shipping routes and is available for operation in place.